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@MannLabs

Mann Labs

MannLabs

We develop open-source software for MS-based proteomics, driven by teams at the Max Planck Institute of Biochemistry and the Centre for Proteomics Research (Copenhagen).

Our aim is to provide flexible and future-proof tools for proteomics that span the full data analysis pipeline - from efficient access to raw MS data, through peptide and protein identification and quantification, to biological interpretation and multi-omics integration. We pursue this through:

  • Open science: all software is released under permissive open-source licenses
  • Reproducibility and scientific quality: performant, well-tested, and well-documented methods
  • Accessibility: clear APIs, tutorials, and contribution guidelines
  • Community collaboration: tools designed to be extensible and interoperable

Learn more at https://alphapept.org or reach out on GitHub!

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  1. alphadia alphadia Public

    modular & open DIA search

    Jupyter Notebook 96 9

  2. alphapeptdeep alphapeptdeep Public

    Deep learning framework for proteomics

    Jupyter Notebook 140 23

  3. CKG CKG Public

    Clinical Knowledge Graph (CKG) is a platform with twofold objective: 1) build a graph database with experimental data and data imported from diverse biomedical databases 2) automate knowledge disco…

    Jupyter Notebook 572 121

  4. alphapept alphapept Public

    A modular, python-based framework for mass spectrometry. Powered by nbdev.

    HTML 184 34

  5. alphatims alphatims Public

    An open-source Python package for efficient accession and visualization of Bruker TimsTOF raw data from the Mann Labs at the Max Planck Institute of Biochemistry.

    Python 92 30

  6. alphamap alphamap Public

    An open-source Python package for the visual annotation of proteomics data with sequence specific knowledge.

    Jupyter Notebook 90 21

Repositories

Showing 10 of 55 repositories
  • research-highlights Public

    MannLabs research highlights in one place

    MannLabs/research-highlights’s past year of commit activity
    HTML 0 CC-BY-SA-4.0 1 0 0 Updated Dec 23, 2025
  • alphadia Public

    modular & open DIA search

    MannLabs/alphadia’s past year of commit activity
    Jupyter Notebook 96 Apache-2.0 9 14 7 Updated Dec 23, 2025
  • alphakraken Public

    A fully automated data processing and analysis system for mass spectrometry experiments.

    MannLabs/alphakraken’s past year of commit activity
    Python 5 Apache-2.0 0 0 1 Updated Dec 23, 2025
  • scPortrait Public

    scPortrait is a scalable toolkit to generate single-cell representations from raw microscopy images

    MannLabs/scPortrait’s past year of commit activity
    Python 104 Apache-2.0 6 25 4 Updated Dec 22, 2025
  • directlfq Public

    Fast and accurate label-free quantification for small and very large numbers of proteomes

    MannLabs/directlfq’s past year of commit activity
    Jupyter Notebook 60 Apache-2.0 7 6 2 Updated Dec 22, 2025
  • MannLabs/alphadia-search-rs’s past year of commit activity
    Rust 0 Apache-2.0 0 0 2 Updated Dec 22, 2025
  • alphapepttools Public

    Search- and quantification-engine agnostic biological interpretation of proteomics data

    MannLabs/alphapepttools’s past year of commit activity
    Python 9 Apache-2.0 1 2 6 Updated Dec 19, 2025
  • .github Public
    MannLabs/.github’s past year of commit activity
    0 1 0 0 Updated Dec 19, 2025
  • alphabase Public

    Infrastructure of AlphaX ecosystem

    MannLabs/alphabase’s past year of commit activity
    Python 51 Apache-2.0 13 7 12 Updated Dec 17, 2025
  • alphapeptdeep Public

    Deep learning framework for proteomics

    MannLabs/alphapeptdeep’s past year of commit activity
    Jupyter Notebook 140 Apache-2.0 23 22 3 Updated Dec 17, 2025